February 2, 2017

Formation of α-chiral centers by asymmetric β-C(sp 3 )–H arylation, alkenylation, and alkynylation

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Resumen

)-H bonds of one of the prochiral methyl groups. We detail the enantioselective β-arylation, -alkenylation, and -alkynylation of isobutyric acid/2-aminoisobutyric acid derivatives, which may serve as a platform for the construction of α-chiral centers.

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Wu et al. (Thu,) studied this question.

synapsesocial.com/papers/6a07e668217278811afe07ff https://doi.org/https://doi.org/10.1126/science.aal5175

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