Key result
Biplane angiocardiography in subjects without significant heart disease demonstrated a mean left atrial maximum volume of 63±16 cc and a cyclic volume change of 33±13 cc.
Why the study?
What are the normal left atrial volumes and cyclic volume changes measured by biplane angiocardiography in subjects without significant heart disease?
Observational (n=22)
What are the normal left atrial volumes and cyclic volume changes measured by biplane angiocardiography in subjects without significant heart disease?
In normal subjects, the left atrium serves mainly as a reservoir and conduit, with its cyclic volume change constituting 38% of LV stroke volume.
Offers normative LA volumes by biplane angiography in healthy subjects; leaves open validation with modern imaging in contemporary cohorts.
Maximum and minimum volumes of the left atrium (LA) were calculated from the biplane angiocardiograms of 18 men and four women without significant heart disease. The mean LA maximum volume was 63 cc ± 16 cc; the mean LA minimum volume was 31 cc±10 cc, and their difference, LA cyclic volume change, was 33 cc±13 cc. Larger LA volumes were associated with greater cyclic volume changes. LA cyclic volume changes constituted 38% of LV stroke volume. No significant correlation between LA volumes and age, sex, surface area, heart rate, LV end-diastolic volume, LV stroke volume, or cardiac output was found. Volume data in normal subjects support the thesis that the LA serves mainly as a reservoir and conduit for blood destined for the left ventricle and that its contractile function is less important. The relation of LA volume change to LV stroke volume appears abnormal in chronic mitral regurgitation and constrictive pericarditis.
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Murray et al. (1968) conducted an observational in Without significant heart disease (n=22). Biplane angiocardiography was evaluated on Left atrial maximum and minimum volumes and cyclic volume change. Biplane angiocardiography in subjects without significant heart disease demonstrated a mean left atrial maximum volume of 63±16 cc and a cyclic volume change of 33±13 cc.
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