Why the study?
Symptom burden and disease effects following myocardial infarction with nonobstructive coronary arteries (MINOCA) are not well studied.
Do patients with MINOCA have a higher prevalence of angina pectoris, sick leave, and worse quality of life at 1 year compared to patients with MI-CAD?
Do patients with MINOCA have a higher prevalence of angina pectoris, sick leave, and worse quality of life at 1 year compared to patients with MI-CAD?
Patients with MINOCA experience significant distress, including higher angina burden, more sick leave, and worse quality of life at 1 year compared to fully revascularized MI-CAD patients.
Highlights need for symptom-focused care in MINOCA; observational data leave open efficacy of targeted therapies.
BACKGROUND: Symptom burden and disease effects following myocardial infarction with nonobstructive coronary arteries (MINOCA) are not well studied. We aimed to evaluate the prevalence of angina pectoris, sick leave, and quality-of-life levels 1 year after the index event, using patients with myocardial infarction due to obstructive coronary artery disease (MI-CAD) as controls. METHODS AND RESULTS: 0.001). Quality-of-life measures were lower in MINOCA. These associations were unaffected when adjusting for angina status but were attenuated when adjusting for potential confounders. CONCLUSIONS: Patients with MINOCA have significant distress, with higher levels of angina pectoris and sick leave and worse quality of life at 1 year compared with fully revascularized MI-CAD counterparts.
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Welén-Schef et al. (2025) studied this question.
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