Key result
Female sex was associated with higher 30-day mortality after acute myocardial infarction compared to male sex (17.6% vs 9.6%; OR 1.39, 95% CI 1.06-1.82), driven by older age and comorbidities.
Why the study?
Does female sex compared to male sex affect the management and mortality outcomes in patients with acute myocardial infarction?
Population
2,867 consecutive acute myocardial infarction patients hospitalized in 25 cardiac care units in Israel from…
Comparison
Female sex vs Male sex
Design
Cohort
Follow-up
1 year
Authors
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Women with AMI may need closer short-term monitoring; leaves open whether modern care mitigates age- and comorbidity-driven risks.
Observational (n=2,867)
Yes
Does female sex compared to male sex affect the management and mortality outcomes in patients with acute myocardial infarction?
Effect estimate: OR 1.39 (95% CI 1.06-1.82)
Absolute Event Rate: 17.6% vs 9.6%
Women with AMI have higher 30-day mortality than men, which appears primarily driven by older age and greater comorbidities rather than differences in the use of therapeutic modalities.
Gottlieb et al. (2000) conducted an observational in Acute myocardial infarction (n=2,867). Female sex vs. Male sex was evaluated on 30-day mortality (OR 1.39, 95% CI 1.06-1.82). Female sex was associated with higher 30-day mortality after acute myocardial infarction compared to male sex (17.6% vs 9.6%; OR 1.39, 95% CI 1.06-1.82), driven by older age and comorbidities.
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