Key result
Adipocyte dysfunction, characterized by imbalanced adipokine production, acts as a common antecedent linking obesity, insulin resistance, and cardiovascular disease.
This review highlights adipocyte dysfunction as a key pathophysiological driver linking obesity, insulin resistance, and cardiovascular disease, suggesting it as a potential therapeutic target.
No takes yet. Share an insight, caveat, or question.
May identify adipocyte dysfunction as a therapeutic target in obesity-related CVD; leaves open whether interventions improve outcomes in trials.
Wassink et al. (2006) conducted a review in Metabolic syndrome and insulin resistance. Adipocyte dysfunction, characterized by imbalanced adipokine production, acts as a common antecedent linking obesity, insulin resistance, and cardiovascular disease.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: