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February 1, 1991Diabetes Care

Increased Incidence of Type II Diabetes Mellitus in Mexican Americans

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Key result

Mexican Americans had a significantly higher 8-year incidence of type II diabetes compared to non-Hispanic whites (6.5% vs 2.0%; adjusted OR 2.72, 95% CI 1.02-7.28).

Why the study?

Does Mexican American ethnicity increase the incidence of type II diabetes mellitus compared to non-Hispanic whites?

Population

923 participants from the San Antonio Heart Study, a population-based study of diabetes and cardiovascular…

Comparison

Mexican American ethnicity vs Non-Hispanic white ethnicity

Design

Cohort

Follow-up

8 years

Authors

Steven M. HaffnerSteven M. HaffnerUniversité Paris-SudHHHelen P. HazudaGeneral / Preventive / LipidsBraxton D. MitchellBraxton D. MitchellGeneral / Preventive / Lipids

Discussion

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Member takes

Implication

May support ethnicity-specific diabetes screening; leaves open causal pathways for prospective confirmation.

Study Design

Type

Cohort (n=923)

Structured PICO

Does Mexican American ethnicity increase the incidence of type II diabetes mellitus compared to non-Hispanic whites?

P
Population
923 participants (617 Mexican Americans and 306 non-Hispanic whites) from the San Antonio Heart Study, a population-based study of diabetes and cardiovascular disease.
I
Intervention
Mexican American ethnicity (observational exposure)
C
Comparator
Non-Hispanic white ethnicity
O
Outcome
8-year incidence of type II diabetes mellitus (defined by World Health Organization criteria)

Main Result

Effect estimate: OR 2.72 (95% CI 1.02-7.28)

Absolute Event Rate: 6.5% vs 2%

Mexican Americans have a significantly higher 8-year incidence of type II diabetes compared to non-Hispanic whites, independent of obesity, age, or education level.

Cite This Study

Haffner et al. (1991) conducted a cohort in Type II diabetes mellitus (n=923). Mexican American ethnicity vs. Non-Hispanic white ethnicity was evaluated on 8-year incidence of type II diabetes (OR 2.72, 95% CI 1.02-7.28). Mexican Americans had a significantly higher 8-year incidence of type II diabetes compared to non-Hispanic whites (6.5% vs 2.0%; adjusted OR 2.72, 95% CI 1.02-7.28).

synapsesocial.com/papers/6a0808cd1e8b9db648ddeaf6https://doi.org/10.2337/diacare.14.2.102
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1DIABETES AMONG MEXICAN AMERICANS IN STARR COUNTY, TEXAS1983 · 166 citations
  2. 2Secular trends in ischemic heart disease and stroke mortality from 1970 to 1976 in Spanish-surnamed and other white individuals in Bexar County, Texas.1978 · 36 citations
  3. 3The Influence of Body Fat Distribution on the Incidence of Diabetes Mellitus: 13.5 Years of Follow-up of the Participants in the Study of Men Born in 19131985 · 982 citations
  4. 4Myocardial infarction in Mexican-Americans and non-Hispanic whites. The San Antonio Heart Study.1991 · 112 citations
  5. 5Incidence of Type II Diabetes in Mexican Americans Predicted by Fasting Insulin and Glucose Levels, Obesity, and Body-Fat Distribution1990 · 385 citations