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The aim is to monitor the genetic diversity and lineage dynamics of dengue virus in Thailand to inform public health strategies.

May 16, 2026Virology JournalOpen Access

Dengue virus genetic diversity and lineage dynamics in Thailand: implications for surveillance and vaccine implementation

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Randomized trial monitors dengue virus genetic diversity and lineages in Thailand, indicating impacts for surveillance and vaccination.

The aim is to monitor the genetic diversity and lineage dynamics of dengue virus in Thailand to inform public health strategies.
Sequenced the complete envelope gene from 92 DENV isolates collected from October 2023 to September 2024.
Analyzed DENV sequences retrieved from NCBI for lineage determination and phylogenetic analysis.
Evaluated co-circulation of DENV serotypes and their genotypes over time.
DENV-2 was the dominant serotype (44.57%) among isolates, with shifts observed during outbreaks.
Phylogenetic analysis showed DENV-1 (genotype I), DENV-2 (genotype II and V), and DENV-3 (genotype III) as the major circulating genotypes.
Dengue vaccine strain identified as Thailand 2024 and linked to impacts on current and future DENV circulation.

Sittikul et al. (2026) studied this question.

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