An integrated optofluidic platform enabling label-free single-cell sorting and culture

Baojian Zhang; Fuyuan Chen; Liru Zhao; Mengting Ming; Meina Chen; Chunfang Deng; Yuntong Wang; Huabing Yin; Bei Li; Peng Liang

doi:10.1039/d6an00203j

January 1, 2026The Analyst

An integrated optofluidic platform enabling label-free single-cell sorting and culture

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Key Points

This research aims to enhance single-cell manipulation utilizing an integrated optofluidic platform while addressing fluidic force challenges.
Developed an optofluidic platform employing optical tweezers for single-cell sorting and culture.
Analyzed the impacts of hydrodynamic drag and trapping stability at varying laser power settings.
Demonstrated effective single-cell sorting with reduced fluidic force constraints.
Achieved stable cell culture without the need for labeling or excessive laser power.

Implication

Explores single-cell manipulation and culture using an optofluidic platform, suggesting efficiency improvements.

Abstract

Optical tweezers (OT) technology enables high-precision single-cell manipulation but is fundamentally constrained by the trade-off between hydrodynamic drag and trapping stability; overcoming fluidic forces often requires elevated laser power that...

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a080a9fa487c87a6a40c81c https://doi.org/10.1039/d6an00203j

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An integrated optofluidic platform enabling label-free single-cell sorting and culture

Key Points

Implication

Abstract

Discussion

Cite This Study

An integrated optofluidic platform enabling label-free single-cell sorting and culture

Key Points

Implication

Abstract

Discussion

Cite This Study

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