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February 14, 2026Lab on a Chip2 citationsOpen Access

MaGIC-OT: an AI-guided optical tweezers platform for autonomous single-cell isolation in microfluidic devices

JCJan-Philipp CieslikXXXiaoye XiaASAli Salehi‐Reyhani

Key Points

  • The research focuses on developing an AI-guided platform for efficient single-cell isolation from complex biological samples.
  • Developed MaGIC-OT platform using optical tweezers technology.
  • Implemented automation for single-cell isolation.
  • Utilized microfluidic devices for collision-free transport of cells.
  • Achieved high-purity delivery of rare cells.
  • Successfully isolated single cells without collision in crowded environments.

Abstract

MaGIC-OT automates optical tweezer-based single-cell isolation in microfluidic devices, enabling collision-free transport and high-purity delivery of rare cells from crowded biological samples.

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Cite This Study

Cieslik et al. (2026) studied this question.

synapsesocial.com/papers/699011712ccff479cfe58150https://doi.org/10.1039/d5lc00738k
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