Associations of High‐Sensitivity Cardiac Troponin and N‐Terminal Pro‐B‐Type Natriuretic Peptide With Echocardiographic Features in Patients With Hypertension

Figures

• 

  FIGURE 1. Spearman correlation heatmap showing the correlations between circulating cardiac biomarkers (hs‐cTnT and NT‐proBNP) and echocardiographic features. * p value < 0.0025 (0.05/20) is considered statistically significant after Bonferroni correction. AAD, ascending aorta diameter; ARD, aortic root diameter; AVV, aortic valve velocity; hs‐cTnT, high‐sensitivity cardiac troponin T; IVSd, interventricular septal thickness at end‐diastole; IVSMA, interventricular septum motion amplitude; LAD, left atrial diameter; LVEDD, left ventricular end‐diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end‐systolic diameter; LVFS, left ventricular fractional shortening; LVMI, left ventricular mass index; LVPWd, left ventricular posterior wall thickness at end‐diastole; LVPWMA, left ventricular posterior wall motion amplitude; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; PAD, pulmonary artery diameter; PVV, pulmonary valve velocity; RVEDD, right ventricular end‐diastolic diameter; RVOT, right ventricular outflow tract.

• 

  FIGURE 2. Echocardiographic features associated with each cardiac biomarker. Hs‐cTnT: tertile 1 (<4.15 ng/L); tertile 2 (4.15–6.43 ng/L), tertile 3 (>6.43 ng/L). NT‐proBNP: tertile 1 (≤22.30 ng/L), tertile 2 (22.30–47.40 ng/L), tertile 3 (>47.40 ng/L). The models were adjusted for age, sex, body mass index, systolic blood pressure, heart rate, smoking, diabetes, estimated glomerular filtration rate, heart rate, duration of hypertension, and use of antihypertensive medication. p values were adjusted using the Bonferroni correction for multiple comparisons. LV structure included LVEDD, LVESD, LVMI, and LVPWd. LV systolic included LVEF, LVFS, LVPWMA, and IVSMA. LV diastolic function included E‐peak, A‐peak, and E/A ratio. Large arteries included ARD, AAD, and PAD. Valve velocities included AVV and PVV. Left atrium indicated LAD. Right ventricle included RVEDD and RVOT. Interventricular septum indicated IVSd. AAD, ascending aorta diameter; ARD, aortic root diameter; AVV, aortic valve velocity; hs‐cTnT, high‐sensitivity cardiac troponin T; IVSd, interventricular septal thickness at end‐diastole; IVSMA, interventricular septum motion amplitude; LAD, left atrial diameter; LVEDD, left ventricular…