Key result
Residual LVH after AVR is linked to ~189% higher risk of death and CV hospitalization.
Why the study?
Does residual left ventricular hypertrophy increase the risk of all-cause death and cardiovascular hospitalization in patients with severe aortic stenosis after aortic valve replacement?
Cohort (n=132)
Does residual left ventricular hypertrophy increase the risk of all-cause death and cardiovascular hospitalization in patients with severe aortic stenosis after aortic valve replacement?
Effect estimate: OR 2.89 (95% CI 1.12-7.44)
p-value: p=0.035
Residual left ventricular hypertrophy after aortic valve replacement for severe aortic stenosis is common and associated with a significantly higher risk of death and cardiovascular hospitalization, particularly in women.
No takes yet. Share an insight, caveat, or question.
May warrant closer post-AVR surveillance in severe AS; hypothesis-generating and requires prospective trials before practice change.
Gavina et al. (2015) conducted a cohort in severe aortic stenosis (n=132). Residual left ventricular hypertrophy (LVH) vs. No residual LVH was evaluated on all-cause death and non-fatal cardiovascular hospitalization (OR 2.89, 95% CI 1.12-7.44, p=0.035). Residual LVH after aortic valve replacement was associated with a higher risk of all-cause death and non-fatal cardiovascular hospitalization (OR 2.89; 95% CI 1.12-7.44; P=0.035).
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