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April 2, 1988European Heart Journal

Aortic valve replacement and coronary bypass grafting for patients with aortic stenosis and coronary artery disease: early and late results

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Key result

Aortic valve replacement and bypass grafting for aortic stenosis and coronary artery disease resulted in 4.4% to 5.3% in-hospital mortality, with bioprostheses enhancing late survival.

Why the study?

What are the early and late outcomes of combined aortic valve replacement and coronary bypass grafting in patients with aortic stenosis and coronary artery disease?

Population

669 patients (294 from 1967-1981, 375 from 1981-1986) with aortic stenosis and coronary artery disease

Design

Cohort

Follow-up

up to 10 years

Authors

BLB. W. LytlePurdue University West LafayetteDCD. M. CosgroveCleveland ClinicMGMarlene GoormasticCross-Cutting Cardiology

Discussion

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Implication

Supports combined AVR+CABG feasibility with acceptable risk; extends historical observations on bioprostheses but leaves open relevance to contemporary practice.

Study Design

Type

Cohort (n=669)

Structured PICO

What are the early and late outcomes of combined aortic valve replacement and coronary bypass grafting in patients with aortic stenosis and coronary artery disease?

P
Population
669 patients (294 from 1967-1981, 375 from 1981-1986) with aortic stenosis and coronary artery disease
I
Intervention
Aortic valve replacement (AVR) combined with coronary bypass grafting
O
Outcome
In-hospital mortality and late survival (at 2, 5, and 10 postoperative years)hard clinical

Combined aortic valve replacement and coronary bypass grafting can be performed with acceptable early mortality, with bioprostheses potentially enhancing late and event-free survival.

Cite This Study

Lytle et al. (1988) conducted a cohort in Aortic stenosis and coronary artery disease (n=669). Aortic valve replacement and coronary bypass grafting was evaluated on In-hospital mortality and late survival. Aortic valve replacement and bypass grafting for aortic stenosis and coronary artery disease resulted in 4.4% to 5.3% in-hospital mortality, with bioprostheses enhancing late survival.

synapsesocial.com/papers/6a0827ccab15ea61dee8b206https://doi.org/10.1093/eurheartj/9.suppl_e.143
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Aortic valve replacement combined with myocardial revascularization. Late clinical results and survival of surgically-treated aortic valve patients with and without coronary artery disease.1977 · 46 citations
  2. 2Early and Late Mortality of Patients Undergoing Aortic Valve Replacement After Previous Coronary Artery Bypass Graft Surgery1995 · 85 citations
  3. 3Aortic Valve Replacement With and Without Coronary Artery Bypass Surgery1974 · 57 citations
  4. 4Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and Predictors of Mortality2011 · 2 citations
  5. 5Management of Asymptomatic Aortic Stenosis in Patients Undergoing Coronary Artery Bypass Grafting.2003 · 1 citations