Key result
Adopting myocarditis biomarkers enables early diagnosis and treatment by clarifying disease progression.
Why the study?
Current diagnostic techniques for myocarditis, such as endomyocardial biopsy and imaging, are costly and intrusive, driving interest in reliable and prognostically educative biomarkers.
What are the reliable, accurate, and prognostically educative biomarkers for the early diagnosis and progression of myocarditis?
What are the reliable, accurate, and prognostically educative biomarkers for the early diagnosis and progression of myocarditis?
This review highlights the importance of identifying and adopting reliable biomarkers and imaging techniques for the early diagnosis and management of myocarditis.
May inform biomarker research priorities in myocarditis; leaves open prospective validation before clinical adoption.
INTRODUCTION: Myocarditis is an inflammatory disease of the myocardial layer of the heart that can be prone to dilation of chambers with presentation as heart failure secondary to dilated cardiomyopathy. Myocarditis can lead to remodeling and fibrosis that can affect the heart's relaxation-lusitropy and chronotropic function. The current techniques for identifying myocarditis, such as endomyocardial biopsy and imaging, are costly, and intrusive. The current literature aims to identify reliable, accurate, and prognostically educative biomarkers of myocarditis. AREAS COVERED: This review covers the definition, clinical features, diagnostic markers, cardiac imaging, prognosis, and complications of myocarditis. PubMed, Embase, and the Cochrane data bank were searched from inception to 1 January 2024 for relevant articles. EXPERT OPINION: By adopting these diagnostic and prognostic biomarkers, clinicians can have a better comprehension of the progression of the disease and provide early diagnosis and treatment for myocarditis.
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Sattar et al. (2024) conducted a review in Myocarditis. Diagnostic and prognostic biomarkers was evaluated. Adopting diagnostic and prognostic biomarkers for myocarditis enables early diagnosis and treatment by providing clinicians with a better comprehension of disease progression.
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