Key result
Prior VT/VF linked to ~455% higher SCD risk within 3 months post-revascularization in ischemic LVSD.
Why the study?
The risk of sudden cardiac death after coronary revascularization in patients with left ventricular systolic dysfunction has not been completely characterized.
What is the incidence, time course, and predictors of sudden cardiac death after coronary revascularization in patients with ischemic left ventricular systolic dysfunction?
Cohort (n=2,317)
No
What is the incidence, time course, and predictors of sudden cardiac death after coronary revascularization in patients with ischemic left ventricular systolic dysfunction?
In patients with ischemic left ventricular systolic dysfunction undergoing revascularization, the risk of sudden cardiac death is highest in the first 3 months, driven by history of VT/VF and triple vessel disease rather than preoperative EF.
Answers are grounded in this paper and cite their sources.
May warrant early SCD monitoring post-revascularization in patients with prior VT/VF; hypothesis-generating for risk stratification in ischemic LV systolic dysfunction.
Background: The risk of sudden cardiac death (SCD) after coronary revascularization in patients with left ventricular (LV) systolic dysfunction has not been characterized completely. This study aims to evaluate the incidence and time course of SCD after revascularization in such patients. The determinants of SCD within 3 months after revascularization were also assessed. Methods: 40%), who underwent revascularization was performed. The incidence of SCD was estimated to account for the competing risk of deaths due to other causes. Conclusions: For patients with LV dysfunction, the risk of SCD was the highest during the first 3 months after revascularization. Further risk classification and treatment strategy are warranted. Clinical Trial Registration: The name of the registry: Coronary Revascularization in Patients with Ischemic Heart Failure and Prevention of Sudden Cardiac Death. Registration number: ChiCTR2100044378.
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Wang et al. (2023) conducted a cohort in Ischemic Left Ventricular Systolic Dysfunction (n=2,317). History of VT/VF vs. No history of VT/VF was evaluated on Sudden cardiac death within 3 months after revascularization (HR 5.55, 95% CI 1.33-23.19, p=0.019). A history of ventricular tachycardia or fibrillation increased the risk of sudden cardiac death within 3 months after revascularization in patients with ischemic left ventricular systolic dysfunction.
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