Key result
Moderate to severe depression in patients with heart failure was associated with a 4-fold increase in all-cause mortality (HR 4.06; 95% CI 2.35-7.01) and increased healthcare utilization.
Why the study?
Does depression increase healthcare utilization and mortality in patients with heart failure?
Population
402 patients with heart failure from Olmsted, Dodge, and Fillmore county, Minnesota, mean age 73±13 years…
Comparison
Moderate to severe depression or mild depression vs None to minimal depression (PHQ-9 score 0-4)
Design
Cohort
Follow-up
mean 1.6 years
Authors
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Supports depression screening in HF; hypothesis-generating for whether treatment improves survival.
Cohort (n=402)
Does depression increase healthcare utilization and mortality in patients with heart failure?
Effect estimate: HR 4.06 (95% CI 2.35-7.01)
Moderate to severe depression in heart failure patients is independently associated with significantly increased healthcare utilization and a 4-fold higher risk of all-cause mortality.
Moraska et al. (2013) conducted a cohort in Heart failure (n=402). Moderate to severe depression vs. None to minimal depression was evaluated on All-cause mortality (HR 4.06, 95% CI 2.35-7.01). Moderate to severe depression in patients with heart failure was associated with a 4-fold increase in all-cause mortality (HR 4.06; 95% CI 2.35-7.01) and increased healthcare utilization.
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