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The solubilities of andrographolide in methanol, ethanol, butan-1-ol, propanone, and water over the temperature range of (288.2 to 323.2) K were measured. The solubilities of andrographolide in selected solvents increased with an increase of temperature. The experimental results were fitted with the modified Apelblat equation.
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Chen et al. (2010) studied this question.
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