Key result
Coronary bypass surgery produced sustained improvement in exercise tolerance over 5 years, increasing total work by 39-66% (p<0.02-0.001) when complete revascularization was achieved.
Why the study?
Does coronary bypass surgery improve exercise tolerance compared to medical therapy in patients with angina pectoris?
Population
100 patients with angina pectoris who fulfilled specific entry criteria
Comparison
Coronary bypass surgery vs Medical therapy
Design
RCT, randomly assigned
Follow-up
5 years
Authors
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Supports CABG for sustained functional gains in angina; extends RCT evidence that complete revascularization drives durability.
RCT (n=100)
Does coronary bypass surgery improve exercise tolerance compared to medical therapy in patients with angina pectoris?
p-value: p=<0.02-0.001
Coronary bypass surgery provides sustained improvement in exercise tolerance over 5 years compared to medical therapy, provided complete revascularization is achieved.
Frick et al. (1983) conducted an RCT in angina pectoris (n=100). coronary bypass surgery vs. medical therapy was evaluated on exercise tolerance (total work) (p=<0.02-0.001). Coronary bypass surgery produced sustained improvement in exercise tolerance over 5 years, increasing total work by 39-66% (p<0.02-0.001) when complete revascularization was achieved.
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