Key result
Review summarizes current antithrombotic strategies for secondary prevention in CAD, stenting, and structural heart interventions.
Why the study?
Rapid implementation of novel techniques and devices in percutaneous cardiovascular interventions has driven refined antithrombotic strategies for secondary prevention supported by clinical studies.
This review summarizes current evidence and emphasizes treatment individualization for antithrombotic strategies following percutaneous coronary and structural heart interventions.
Emphasizes individualized antithrombotic therapy post-PCI and structural interventions; leaves optimal regimens open for prospective trials.
Percutaneous cardiovascular interventions have changed dramatically in recent years, and the impetus given by the rapid implementation of novel techniques and devices have been mirrored by a refinement of antithrombotic strategies for secondary prevention, which have been supported by a significant burden of evidence from clinical studies. In the current manuscript, we aim to provide a comprehensive, yet pragmatic, revision of the current available evidence regarding antithrombotic strategies in the domain of percutaneous cardiovascular interventions. We revise the evidence regarding antithrombotic therapy for secondary prevention in coronary artery disease and stent implantation, the complex interrelation between antiplatelet and anticoagulant therapy in patients undergoing percutaneous coronary intervention with concomitant atrial fibrillation, and finally focus on the novel developments in the secondary prevention after structural heart disease intervention. A special focus on treatment individualization is included to emphasize risk and benefits of each therapeutic strategy.
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Caracciolo et al. (2019) conducted a review in Percutaneous cardiovascular interventions. Antithrombotic therapy was evaluated. This review summarizes current evidence regarding antithrombotic strategies for secondary prevention in coronary artery disease, stent implantation, and structural heart disease interventions.
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