Emerging therapeutic targets in heart failure, specifically inflammation, metabolism, and neurohormonal regulation, alongside multi-omics technologies, offer promising avenues for future treatments.
Abstract Recent advancements in signaling pathways and cellular crosstalk have led to a surge in innovative treatments targeting various mechanisms in heart failure. This review explores 3 particularly promising therapeutic targets: inflammation, metabolism, and neurohormonal regulation. These areas have garnered attention due to their potential to improve clinical outcomes and inform translational studies. Furthermore, the integration of high-throughput and multi-omics technologies has significantly advanced the field of cardiovascular regeneration, facilitating its progression toward clinical practice. By examining these mechanisms and the latest research developments, this review aims to provide insights into the future of heart failure therapies and their potential impact on patient care.
Yang et al. (Mon,) conducted a review in Heart failure. Therapeutic targets (inflammation, metabolism, and neurohormonal regulation) was evaluated. Emerging therapeutic targets in heart failure, specifically inflammation, metabolism, and neurohormonal regulation, alongside multi-omics technologies, offer promising avenues for future treatments.