Key result
In a Taiwanese cohort with hypertrophic cardiomyopathy, the annual cardiovascular mortality rate was 0.8%, and left ventricular outflow obstruction was an independent predictor of mortality (OR 4.92).
Population
163 consecutive patients with hypertrophic cardiomyopathy at a medical center in Taiwan from 1990 through…
Design
Cohort
Follow-up
mean 5.3 +/- 4.1 years
Authors
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LVOTO may flag higher-risk HCM patients for monitoring; leaves open whether targeted therapies improve survival.
Cohort (n=163)
No
Effect estimate: OR 4.92
p-value: p=0.001
In a Taiwanese cohort, hypertrophic cardiomyopathy had a low annual cardiovascular mortality rate of 0.8%, but over one-third experienced cardiovascular events, with LV outflow obstruction, atrial fibrillation, and female gender predicting mortality.
Lee et al. (2007) conducted a cohort in Hypertrophic cardiomyopathy (n=163). In a Taiwanese cohort with hypertrophic cardiomyopathy, the annual cardiovascular mortality rate was 0.8%, and left ventricular outflow obstruction was an independent predictor of mortality (OR 4.92).
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