Key result
In patients with apical hypertrophic cardiomyopathy, left atrial enlargement was the only predictor of cardiovascular morbidity (OR 5.85; 95% CI 1.15-29.40; p=0.034), with no mortality observed.
Population
40 patients with apical hypertrophic cardiomyopathy diagnosed by echocardiography in a Taiwan tertiary…
Design
Cohort
Follow-up
mean 72.2 +/- 60.1 months
Authors
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May inform risk stratification by left atrial size in apical HCM; observational data leaves open prospective validation before practice change.
Cohort (n=40)
No
Effect estimate: OR 5.85 (95% CI 1.15-29.40)
p-value: p=0.034
In a Taiwanese cohort, apical hypertrophic cardiomyopathy had a benign mortality course, but left atrial enlargement strongly predicted cardiovascular morbidity such as syncope and stroke-associated atrial fibrillation.
Lee et al. (2006) conducted a cohort in Apical hypertrophic cardiomyopathy (ApHCM) (n=40). Left atrial enlargement was evaluated on Cardiovascular morbidity (OR 5.85, 95% CI 1.15-29.40, p=0.034). In patients with apical hypertrophic cardiomyopathy, left atrial enlargement was the only predictor of cardiovascular morbidity (OR 5.85; 95% CI 1.15-29.40; p=0.034), with no mortality observed.
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