Key result
Patients with hypertrophic cardiomyopathy and atrial fibrillation had significantly smaller left ventricular chamber size and a 7.1% per patient-year incidence of systemic thromboembolism.
Why the study?
Does left ventricular geometry differ between hypertrophic cardiomyopathy patients with and without atrial fibrillation?
Population
92 patients with hypertrophic cardiomyopathy
Comparison
Transient or persistent atrial fibrillation vs Sinus rhythm
Design
Cohort
Authors
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Smaller LV size was associated with AF and high thromboembolism risk in HCM; leaves open whether geometry informs arrhythmia or anticoagulation strategies.
Observational (n=92)
Does left ventricular geometry differ between hypertrophic cardiomyopathy patients with and without atrial fibrillation?
In patients with hypertrophic cardiomyopathy, smaller left ventricular chamber size is associated with atrial fibrillation, which carries a high risk of systemic thromboembolism warranting prophylactic anticoagulation.
Shigematsu et al. (1995) conducted an observational in Hypertrophic cardiomyopathy (n=92). Atrial fibrillation vs. Sinus rhythm was evaluated on Left ventricular chamber size and systemic thromboembolism. Patients with hypertrophic cardiomyopathy and atrial fibrillation had significantly smaller left ventricular chamber size and a 7.1% per patient-year incidence of systemic thromboembolism.
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