Key result
Smoking linked to ~564% greater mortality risk in hypertensive patients, alongside obesity and comorbidities.
Why the study?
Hypertension remains poorly controlled despite effective treatments, leading to complications and death, prompting an assessment of time to death and its predictors in adult hypertensive patients in Dire Dawa, Ethiopia.
Cohort (n=511)
Yes
Factors such as education, medication adherence, lifestyle choices, and comorbidities significantly influence mortality among hypertensive patients in Ethiopia.
Background: Hypertension is a significant global health issue, including in Ethiopia, where it remains poorly controlled despite effective treatments, leading to complications and death. This study aimed to estimate time to death and identify predictors among adult hypertensive patients in Dire Dawa, Ethiopia. Method: -value of <0.05 was considered significant. Results: The median survival time was 24 months, with a mortality rate of 7.9 per 1000 person-months. Significant independent predictors of mortality included higher education (AHR: 0.17), use of amlodipine (AHR: 0.19), combining amlodipine and hydrochlorothiazide (AHR: 0.17), smoking (AHR: 6.64), alcohol consumption (AHR: 2.66), obesity (AHR: 5.55), being overweight (AHR: 5.66), and having comorbidities (AHR: 3.84). Conclusion: Factors such as education, medication adherence, lifestyle choices, and comorbidities significantly influence mortality among hypertensive patients. Comprehensive management strategies addressing these risk factors are crucial for improving survival in similar healthcare settings.
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Ahmed et al. (2025) conducted a cohort in Hypertension (n=511). Risk factors (smoking, alcohol, obesity, comorbidities) vs. Absence of risk factors was evaluated on Time to death (all-cause mortality). Among adult hypertensive patients in Eastern Ethiopia, the mortality rate was 7.9 per 1000 person-months, with smoking (AHR 6.64), obesity (AHR 5.55), and comorbidities (AHR 3.84) significantly predicting time to death.
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