Key result
In STEMI patients, left atrial fractional change assessed by CMR was independently associated with MACE (adjusted HR 0.66; 95% CI 0.46-0.95) and provided incremental prognostic value over LAmax.
Why the study?
Does LA fractional change measured by CMR predict MACE in patients following STEMI?
Cohort (n=199)
Does LA fractional change measured by CMR predict MACE in patients following STEMI?
Effect estimate: adjusted HR 0.66 (95% CI 0.46-0.95)
Impaired LA fractional change measured by CMR provides incremental prognostic information for MACE beyond established predictors including LA maximal volume in STEMI patients.
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May refine post-STEMI risk stratification beyond LA volume; hypothesis-generating and requires prospective validation before practice change.
Lonborg et al. (2012) conducted a cohort in ST elevation myocardial infarction (STEMI) (n=199). Left atrial (LA) fractional change assessment by CMR vs. LA maximal volume (LAmax) was evaluated on Major adverse cardiac event (MACE) including death, re-infarction, stroke, and admission for heart failure (adjusted HR 0.66, 95% CI 0.46-0.95). In STEMI patients, left atrial fractional change assessed by CMR was independently associated with MACE (adjusted HR 0.66; 95% CI 0.46-0.95) and provided incremental prognostic value over LAmax.