Why the study?
Does the magnitude of sympathetic hyperactivity differ between anterior and inferior uncomplicated acute myocardial infarction?
Population
39 patients with uncomplicated acute myocardial infarction and 20 normal subjects matched for age and body…
Comparison
Anterior acute myocardial infarction vs Inferior acute myocardial infarction and normal…
Design
Cohort
Follow-up
2 to 4 days after AMI
Authors
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Does not implicate sympathetic hyperactivity in anterior AMI's worse prognosis; leaves open alternative mechanisms in uncomplicated cases.
Does the magnitude of sympathetic hyperactivity differ between anterior and inferior uncomplicated acute myocardial infarction?
Anterior and inferior uncomplicated AMI result in a similar magnitude of sympathetic nerve hyperactivity, suggesting that the worse prognosis of anterior AMI is not primarily driven by sympathetic overactivation.
Graham et al. (2004) studied this question.
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