Why the study?
Does prophylactic therapy with antiarrhythmic agents reduce mortality in patients with myocardial infarction?
Does prophylactic therapy with antiarrhythmic agents reduce mortality in patients with myocardial infarction?
In patients with myocardial infarction, prophylactic use of class I antiarrhythmic agents increases mortality, whereas beta-blockers and amiodarone reduce mortality.
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Class I agents warrant avoidance post-MI; confirms mortality reduction with beta-blockers and amiodarone.
K. K. Teo (1993) studied this question.