Short-term exercise (as few as five consecutive days) can rapidly induce a cardioprotective phenotype against ischemia-reperfusion injury.
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Hypothesis-generating for rapid exercise cardioprotection; prospective human trials needed before clinical adoption.
Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on consecutive days can rapidly produce a cardiac phenotype that resists IR-induced myocardial injury. This review summarizes the development of exercise-induced cardioprotection and the mechanisms responsible for this important adaptive response.
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Powers et al. (2014) studied this question.
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