Short-term exercise (as few as five consecutive days) can rapidly induce a cardioprotective phenotype against ischemia-reperfusion injury.
Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on consecutive days can rapidly produce a cardiac phenotype that resists IR-induced myocardial injury. This review summarizes the development of exercise-induced cardioprotection and the mechanisms responsible for this important adaptive response.
Powers et al. (Wed,) studied this question.