Key result
Residual congestion at discharge affects >50% of AHF patients and strongly predicts future CV events.
Why the study?
Congestion is the primary cause of hospital admissions and mortality in AHF, yet achieving complete decongestion remains challenging with more than half of patients experiencing residual congestion at discharge.
Residual congestion remains a major challenge in acute heart failure, necessitating tailored diagnostic and therapeutic strategies to achieve complete decongestion.
May prompt enhanced discharge evaluation in acute HF; leaves open optimal decongestion strategies for randomized trials.
Congestion not only represents a cardinal sign of heart failure (HF) but is also now recognized as the primary cause of hospital admissions, rehospitalization, and mortality among patients with acute heart failure (AHF). Congestion can manifest through various HF phenotypes in acute settings: volume overload, volume redistribution, or both. Recognizing the congestion phenotype is paramount, as it implies different therapeutic strategies for decongestion. Among patients with AHF, achieving complete decongestion is challenging, as more than half still experience residual congestion at discharge. Residual congestion is one of the strongest predictors of future cardiovascular events and poor outcomes. Through this review, we try to provide a better understanding of the congestion phenomenon among patients with AHF by highlighting insights into the pathophysiological mechanisms behind congestion and new diagnostic and management tools to achieve and maintain efficient decongestion.
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Mocan et al. (2024) conducted a review in Acute heart failure. Residual congestion at discharge affects >50% of patients with acute heart failure and serves as a strong predictor of future cardiovascular events and poor outcomes.
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