Key result
Surgical treatment for Wolff-Parkinson-White syndrome achieved an initial clinical cure rate of 88%, increasing to 97% with subsequent procedures, with no perioperative or late mortality.
Why the study?
Does surgical treatment for accessory atrioventricular connections improve clinical cure in patients with Wolff-Parkinson-White syndrome?
Cohort (n=60)
Does surgical treatment for accessory atrioventricular connections improve clinical cure in patients with Wolff-Parkinson-White syndrome?
Surgical treatment for Wolff-Parkinson-White syndrome is highly effective and safe, offering a high probability of clinical cure and avoidance of lifelong antiarrhythmic therapy.
Supports surgical referral for refractory WPW; leaves open comparative efficacy versus catheter ablation in randomized trials.
Surgical treatment for accessory atrioventricular connections was performed in 60 patients with Wolff-Parkinson-White syndrome between 1981 and 1986. The initial procedure successfully divided 69 of 73 pathways identified preoperatively, including 39 of 40 left free wall pathways, 23 of 24 posteroseptal pathways, six of seven right free wall pathways, and one of two anteroseptal pathways. Three additional pathways were identified for the first time during follow-up. The primary procedure was successful in curing 53 (88%) of the 60 patients and in dividing 69 (91%) of the total of 76 pathways. Subsequent procedures increased the overall clinical cure rate to 97%. The surgery was performed with low morbidity and no perioperative or late mortality. Patients were followed-up for a mean of 6.4 years (range four to nine years). No patient showed clinical or electrocardiographic evidence of recurrence of a pathway which had been divided surgically. We conclude that regardless of pathway site, surgical treatment carries a low risk and has a high probability of avoiding lifelong antiarrhythmic therapy.
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Rosenfeldt et al. (1991) conducted a cohort in Wolff-Parkinson-White syndrome (n=60). Surgical treatment for accessory atrioventricular connections was evaluated on Clinical cure rate (primary procedure). Surgical treatment for Wolff-Parkinson-White syndrome achieved an initial clinical cure rate of 88%, increasing to 97% with subsequent procedures, with no perioperative or late mortality.
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