Key result
Functional substrate mapping remains essential for treating VT in SHD despite lacking a consensus definition.
Why the study?
A consensus on the definition of functional substrate mapping remains elusive, hindering a structured approach to research.
This review clarifies the definitions and differences in functional substrate mapping techniques for ventricular tachycardia to guide future research and ablation strategies.
May inform VT ablation in structural heart disease; leaves open standardized definitions for future research.
Functional substrate mapping has emerged as an essential tool for electrophysiologists, overcoming many limitations of conventional mapping techniques and demonstrating favourable long-term outcomes in clinical studies. However, a consensus on the definition of 'functional substrate' mapping remains elusive, hindering a structured approach to research in the field. In this review, we highlight the differences between 'functional mapping' techniques (which assess tissue response to the 'electrophysiological stress' using short coupled extrastimuli) and those highlighting regions of slow conduction during sinus rhythm. We also address fundamental questions, including the optimal degree of electrophysiological stress that best underpins the critical isthmus and the role of wavefront activation in determining the most effective ablation site.
No takes yet. Share an insight, caveat, or question.
Al-Sheikhli et al. (2024) conducted a review in Ventricular Tachycardia in Structural Heart Disease. Functional substrate mapping was evaluated. Functional substrate mapping is an essential tool for treating ventricular tachycardia in structural heart disease, though a consensus on its definition remains elusive.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: