Key result
Standardization of Thrombotest at individual hospitals showed significant diversion due to technical errors, suggesting calibration should only occur in specialist coagulation centers.
Why the study?
Is the nationally adopted standardization procedure reliable for comparing the British Comparative Thromboplastin and Thrombotest at individual hospitals?
Population
Standardization procedures at individual hospitals and specialist coagulation centres
Comparison
Thrombotest vs British Comparative Thromboplastin
Design
Other
Authors
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Technical errors undermine hospital Thrombotest standardization; leaves open optimal centralization for reliable calibration.
Observational
Yes
Is the nationally adopted standardization procedure reliable for comparing the British Comparative Thromboplastin and Thrombotest at individual hospitals?
Calibration of Thrombotest against the British Comparative Thromboplastin should be restricted to specialist coagulation centres due to technical errors at individual hospitals.
Poller et al. (1971) conducted an observational in Anticoagulant control. Thrombotest vs. British Comparative Thromboplastin was evaluated on Reliability of comparison between British Comparative Thromboplastin and Thrombotest. Standardization of Thrombotest at individual hospitals showed significant diversion due to technical errors, suggesting calibration should only occur in specialist coagulation centers.
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