Key result
VT ablation in nonischemic cardiomyopathy patients with isolated potentials resulted in 67% remaining arrhythmia-free, compared to 7% in those without isolated potentials (P<0.01).
Why the study?
Does the presence of isolated potentials (IPs) in conjunction with pace-mapping improve ablation outcomes and arrhythmia-free survival in patients with ventricular tachycardia and nonischemic cardiomyopathy?
Population
35 consecutive patients with ventricular tachycardia and various etiologies of nonischemic cardiomyopathy.
Comparison
Mapping and ablation of ventricular tachycardia… vs Patients without isolated potentials compared to…
Design
Cohort
Follow-up
mean 18 ± 13 months
Authors
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May guide ablation targets in nonischemic cardiomyopathy VT; leaves open need for randomized confirmation.
Observational (n=35)
Does the presence of isolated potentials (IPs) in conjunction with pace-mapping improve ablation outcomes and arrhythmia-free survival in patients with ventricular tachycardia and nonischemic cardiomyopathy?
Absolute Event Rate: 67% vs 7%
p-value: p=< 0.01
The presence of isolated potentials during sinus rhythm identifies critical isthmus areas for VT ablation in nonischemic cardiomyopathy and is associated with significantly higher arrhythmia-free survival.
Kühne et al. (2010) conducted an observational in Ventricular tachycardia in nonischemic cardiomyopathy (n=35). Ablation guided by isolated potentials (IPs) and pace-mapping vs. Absence of isolated potentials (IP-negative) was evaluated on Remaining arrhythmia-free during follow-up (p=< 0.01). VT ablation in nonischemic cardiomyopathy patients with isolated potentials resulted in 67% remaining arrhythmia-free, compared to 7% in those without isolated potentials (P<0.01).
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