Key result
Systemic hypertension in adults with hypertrophic cardiomyopathy was associated with a higher prevalence of systolic anterior motion with dynamic LV outflow obstruction (52% vs 19%; P=.02).
Why the study?
Does overlapping systemic hypertension affect clinical characteristics and echocardiographic findings in adults with hypertrophic cardiomyopathy?
Population
196 adults with hypertrophic cardiomyopathy (HCM) evaluated between 1995 and 2005
Comparison
Presence of systemic hypertension (n=122) vs Absence of systemic hypertension (n=74)
Design
Cohort
Authors
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Should not yet change HCM management; leaves open hypertension's role in obstruction.
Observational (n=196)
No
Does overlapping systemic hypertension affect clinical characteristics and echocardiographic findings in adults with hypertrophic cardiomyopathy?
Absolute Event Rate: 52% vs 19%
p-value: p=.02
Systemic hypertension frequently coexists with HCM in adults and is associated with older age, higher risk of diabetes, coronary artery disease, and specific echocardiographic abnormalities like systolic anterior motion of the mitral valve.
Aslam et al. (2010) conducted an observational in Hypertrophic cardiomyopathy (n=196). Systemic hypertension vs. No systemic hypertension was evaluated on Systolic anterior motion of the anterior mitral valve in association with dynamic left ventricular outflow obstruction (p=.02). Systemic hypertension in adults with hypertrophic cardiomyopathy was associated with a higher prevalence of systolic anterior motion with dynamic LV outflow obstruction (52% vs 19%; P=.02).
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