Five-year echocardiographic results of combined undersized mitral ring annuloplasty and coronary artery bypass grafting for chronic ischaemic mitral regurgitation
Key result
Undersized annuloplasty plus CABG for ischemic MR linked to significant 5-year recurrence despite early stability.
- P<0.001
- n=251
Design
Prospective single-centre cohort study
Follow-up
Median 32.9 months
Authors
Discussion
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Implication
High MR recurrence after UMRA plus CABG cautions against routine use; leaves open whether better selection or techniques improve durability.
Study Design
Type
Cohort (n=251)
Multicenter
No
Structured PICO
P
Population
251 patients with chronic ischaemic mitral regurgitation (CIMR), mean age 68.4 +/- 8.1, 62.5% male, single-center (Italy).
I
Intervention
Combined undersizing mitral ring annuloplasty (UMRA) and coronary artery bypass grafting (CABG)
O
Outcome
Echocardiographic results (mitral regurgitation severity, ventricular dimensions, sphericity index) up to 5 yearssurrogate
Main Result
p-value: p=<0.001
Combined undersizing mitral ring annuloplasty and CABG for chronic ischemic mitral regurgitation is associated with significant recurrence of mitral regurgitation and adverse ventricular remodeling at 3 to 5 years.
Cite This Study
Gelsomino et al. (2007) conducted a cohort in Chronic ischaemic mitral regurgitation (CIMR) (n=251). Combined undersizing mitral ring annuloplasty (UMRA) and coronary artery bypass grafting (CABG) was evaluated on Echocardiographic mitral regurgitation (MR) recurrence at 5 years (p=<0.001). Combined undersized mitral ring annuloplasty and CABG for chronic ischemic mitral regurgitation resulted in MR that was stable at 1 year but significantly re-increased at 3 and 5 years (P<0.001).