Key result
Adding regional left ventricular function assessment to cardiac CT significantly improved the overall diagnostic accuracy for acute coronary syndrome (c-statistic 0.88 vs 0.79 for stenosis; P<0.03).
Why the study?
Does adding regional left ventricular function assessment to coronary computed tomography improve the diagnostic accuracy for acute coronary syndrome in patients with acute chest pain?
Observational (n=356)
Double-blind
Does adding regional left ventricular function assessment to coronary computed tomography improve the diagnostic accuracy for acute coronary syndrome in patients with acute chest pain?
Effect estimate: c-statistic
Absolute Event Rate: 0.88% vs 0.79%
p-value: p=<0.03
Adding regional left ventricular function assessment to coronary CT angiography significantly improves diagnostic accuracy for acute coronary syndrome in patients with acute chest pain.
No takes yet. Share an insight, caveat, or question.
May support adding regional LV function to CT for ACS evaluation in acute chest pain; extends prior data but leaves open need for prospective validation.
Seneviratne et al. (2010) conducted an observational in Acute chest pain with inconclusive initial emergency department evaluation (n=356). Regional left ventricular function (LVF) assessment added to cardiac computed tomography vs. Coronary assessment by cardiac computed tomography alone was evaluated on Overall diagnostic accuracy (c-statistic) for detection of acute coronary syndrome (c-statistic, p=<0.03). Adding regional left ventricular function assessment to cardiac CT significantly improved the overall diagnostic accuracy for acute coronary syndrome (c-statistic 0.88 vs 0.79 for stenosis; P<0.03).
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