Key result
Mechanical thrombectomy improves neurological outcomes in a rare case of cerebral embolism from LA metastasis.
Case Report (n=1)
Mechanical thrombectomy can improve neurological outcomes in cancer-related cerebral embolism and provide tissue for histopathological diagnosis of the underlying malignancy.
May support thrombectomy in rare cancer-related emboli; leaves open broader efficacy and practice change.
We present a rare case of cancer-related cerebral embolism (CRCE) caused by left atrial metastasis from renal cell carcinoma. A woman in her 60s presented with acute right-sided hemiparesis and aphasia. CT angiography shows left middle cerebral artery occlusion. The patient underwent thrombolysis and mechanical thrombectomy, resulting in significant neurological improvement. The retrieved thrombus was atypical, white and elastic. Further investigation revealed left atrial and bilateral renal masses. Histopathological examination confirmed metastatic renal cell carcinoma in the left atrium, with the retrieved thrombus containing tumour cells. This is an extremely rare case of CRCE caused by cardiac tumour metastasis from renal cell carcinoma without obvious lung involvement. Histopathological examination of the retrieved thrombus revealed tumour embolism. This case demonstrates that mechanical thrombectomy improves neurological outcomes, and the pathologic findings of the retrieved thrombus will help to diagnose the cause of cerebral infarction.
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Tanaka et al. (2025) conducted a case report in Cancer-related cerebral embolism (n=1). Thrombolysis and mechanical thrombectomy was evaluated on Neurological improvement and histopathological diagnosis. Mechanical thrombectomy improved neurological outcomes in a rare case of cancer-related cerebral embolism caused by left atrial metastasis from renal cell carcinoma.
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