Key result
Breathing hypoxic air (FI(O2) 0.10) significantly prolonged phosphocreatine recovery time constants in sedentary subjects (47.0 s) compared to normoxia (30.0 s) and hyperoxia (31.8 s).
Why the study?
Does varying inspired O2 fraction affect phosphocreatine recovery time in sedentary humans?
Population
6 sedentary human subjects
Comparison
Breathing different fractions of inspired O2 (FI… vs Within-subject comparison across the three FI…
Design
Other
Follow-up
5 min of recovery
Authors
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Mitochondrial capacity, not O2 supply, limits oxidative rate in sedentary muscle under normoxia; extends distinction from trained individuals.
Does varying inspired O2 fraction affect phosphocreatine recovery time in sedentary humans?
Absolute Event Rate: 47% vs 30%
In sedentary humans, maximal muscle oxidative rate is limited by mitochondrial capacity rather than O2 availability in normoxia, unlike in exercise-trained individuals.
Haseler et al. (2004) studied Sedentary humans (n=6). Fraction of inspired O2 (FI(O2)) variation vs. Normoxia (FI(O2) 0.21) was evaluated on Phosphocreatine (PCr) recovery time constants. Breathing hypoxic air (FI(O2) 0.10) significantly prolonged phosphocreatine recovery time constants in sedentary subjects (47.0 s) compared to normoxia (30.0 s) and hyperoxia (31.8 s).
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