Why the study?
Do the time constants of phosphocreatine and oxygenated haemoglobin during recovery from exercise differ between patients with chronic heart failure and normal controls?
Population
13 patients with chronic heart failure and 15 normal controls (total n=28)
Comparison
Calf plantar flexion for six minutes at a… vs Normal subjects performing the same exercise
Design
Case-control
Authors
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Prolonged PCr and oxy-Hb recovery times in heart failure may reflect impaired oxygen utilization; leaves open whether this guides targeted exercise or metabolic interventions.
Do the time constants of phosphocreatine and oxygenated haemoglobin during recovery from exercise differ between patients with chronic heart failure and normal controls?
In patients with chronic heart failure, muscle metabolic recovery appears to depend more on oxygen utilization than on hemoglobin resaturation or oxygen delivery.
Hanada et al. (2000) studied this question.
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