Why the study?
Does percutaneous left atrial appendage occlusion prevent stroke compared to oral anticoagulation in patients with atrial fibrillation?
Does percutaneous left atrial appendage occlusion prevent stroke compared to oral anticoagulation in patients with atrial fibrillation?
This systematic review summarizes current evidence supporting percutaneous LAAO as a viable alternative to oral anticoagulation for stroke prevention in high-risk AF patients.
Supports LAAO as OAC alternative in AF; reinforces consensus from randomized evidence for broader adoption.
Over the past two decades, percutaneous left atrial appendage occlusion (LAAO) has proven to be a viable alternative to oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation (AF), in particular in those patients who are at increased risk for stroke and bleeding complications. This systematic review provides a comprehensive evaluation of anatomical features, patient selection, procedural planning and execution, complications, medical treatment following the procedure, and contemporary outcome data.
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Loria et al. (2023) studied this question.
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