Key result
Men in the highest quintile of the TC/HDL-C ratio had a 54% increased risk of developing incident hypertension compared with those in the lowest quintile over 14.1 years.
Why the study?
Does dyslipidemia predict the development of incident hypertension in men free of baseline hypertension and CVD?
Cohort (n=3,110)
Does dyslipidemia predict the development of incident hypertension in men free of baseline hypertension and CVD?
Effect estimate: HR 1.54
Elevated baseline lipid levels, including total cholesterol, non-HDL-C, and TC/HDL-C ratio, independently predict the subsequent development of incident hypertension in men.
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High TC/HDL-C ratio was associated with incident hypertension in men; leaves open whether lipid modification prevents onset.
Halperin et al. (2005) conducted a cohort in Dyslipidemia and incident hypertension (n=3,110). Highest quintile of TC, non-HDL-C, and TC/HDL-C ratio vs. Lowest quintile was evaluated on Incident hypertension (HR 1.54). Men in the highest quintile of the TC/HDL-C ratio had a 54% increased risk of developing incident hypertension compared with those in the lowest quintile over 14.1 years.
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