Key result
Elevated cardiac troponin predicts higher morbidity and mortality in geriatric patients without ACS.
Why the study?
Interpreting elevated cardiac troponin in geriatric patients without acute coronary syndrome poses a diagnostic dilemma, and elderly patients have not been conclusively included in studies evaluating comorbidity-related increases.
Does elevated cardiac troponin predict all-cause morbidity and mortality in elderly hospitalized patients without acute coronary syndrome?
Systematic Review
Does elevated cardiac troponin predict all-cause morbidity and mortality in elderly hospitalized patients without acute coronary syndrome?
Elevated cardiac troponin serves as an independent prognostic factor for all-cause morbidity and mortality in elderly hospitalized patients without acute coronary syndrome.
Supports troponin for risk stratification in geriatric inpatients without ACS; confirms independent prognostic value via systematic synthesis.
Comorbidities are common risk factors for rising cardiac troponin in non-acute coronary syndromes conditions. Furthermore, the risk for all-cause mortality appears to be correlated to the troponin levels. Consequently, measurement of cardiac troponin in hospital admission may contribute to predict the mortality risk in elderly patients. Among geriatric patients without acute coronary syndrome, with concomitant diseases, the correct interpretation of elevated cardiac troponin, particularly in emergency conditions poses a diagnostic dilemma. Although in several studies it is suggested that at the presence of comorbidity, there is an increase in cardiac troponin values, the elderly patients have not been included conclusively. In order to assess the diagnostic and prognostic role of cardiac troponin elevation in geriatric patients suffering from chronic diseases, a systematic review was performed. The study included the elderly patients free of acute coronary syndrome admitted to the hospital with concomitant disease, with a report of at least one cardiac troponin measurement. We found that elevated cardiac troponin is an independent prognostic factor, predicting all-cause morbidity and mortality burden in geriatric patients without acute coronary syndromes.
No takes yet. Share an insight, caveat, or question.
Sedighi et al. (2020) conducted a systematic review in Geriatric patients without acute coronary syndrome. Elevated cardiac troponin was evaluated on All-cause morbidity and mortality. Elevated cardiac troponin is an independent prognostic factor predicting all-cause morbidity and mortality burden in geriatric patients without acute coronary syndromes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: