Why the study?
Most studies on elevated hs-cTn in elderly populations have focused on specific diagnoses or comorbidity relationships, rather than in-hospital prognosis in non-cardiac admissions.
In elderly patients admitted for non-cardiac reasons with elevated high-sensitivity troponin, severe renal impairment is a marker of extremely high in-hospital mortality.
Severe renal impairment flags high-risk elderly non-cardiac admissions; leaves open whether targeted interventions alter outcomes.
BACKGROUND: High-sensitivity cardiac troponin (hs-cTn) levels are frequently elevated in elderly patients presenting to the emergency department for non-cardiac events. However, most studies on the role of elevated hs-cTn in elderly populations have investigated the prognostic value of hs-cTn in patients with a specific diagnosis or have assessed the relationship between hs-cTn and comorbidities. AIM: To investigate the in-hospital prognosis of consecutive elderly patients admitted to the Internal Medicine Department with acute non-cardiac events and increased hs-cTnI levels. METHODS: In this retrospective study, we selected patients who were aged ≥ 65 years and admitted to the Internal Medicine Department of our hospital between January 2019 and December 2019 for non-cardiac reasons. Eligible patients were those who had hs-cTnI concentrations ≥ 100 ng/L. We investigated the independent predictors of in-hospital mortality by multivariable logistic regression analysis. RESULTS: . CONCLUSION: Myocardial injury is a malignant condition in elderly patients admitted to the hospital for non-cardiac reasons. The presence of severe renal impairment is a marker of extremely high in-hospital mortality.
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Σαμαρά et al. (2021) studied this question.
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