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July 3, 2012Interactive Cardiovascular and Thoracic SurgeryOpen Access

Outcomes of aortic valve repair according to valve morphology and surgical techniques

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Key result

Aortic valve repair resulted in 91.5% overall late survival, with freedom from valve-related events differing significantly between bicuspid and tricuspid valves (P<0.01).

Why the study?

Do aortic valve morphology and specific surgical repair techniques affect long-term clinical outcomes in patients with aortic insufficiency?

Population

216 patients with aortic insufficiency undergoing aortic valve repair, mean age 53 ± 15 years. Valve…

Comparison

Aortic valve repair using various techniques… vs Comparisons between different valve morphologies…

Design

Cohort

Follow-up

mean 42 ± 16 months

Authors

KFKhalil FattouchCardiac SurgeryGMGiacomo MuranaCardiac SurgerySCSebastiano CastrovinciUniversity of Palermo

Discussion

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Implication

Aortic valve repair may warrant morphology-specific caution in aortic insufficiency; this cohort study leaves open randomized comparisons of long-term durability.

Study Design

Type

Observational (n=216)

Multicenter

No

Structured PICO

Do aortic valve morphology and specific surgical repair techniques affect long-term clinical outcomes in patients with aortic insufficiency?

P
Population
216 patients with aortic insufficiency undergoing aortic valve repair, mean age 53 ± 15 years. Valve dysfunctions: type I (25.5%), type II (58.3%), type III (16.2%). 27.7% had bicuspid valves.
I
Intervention
Aortic valve repair using various techniques (sub-commissural plasty, plication, free-edge reinforcement, resection of raphe plus re-suturing, chordae technique) with or without concomitant procedures (e.g., root re-implantation).
C
Comparator
Comparisons between different valve morphologies (bicuspid vs. tricuspid, type I+II vs. type III) and surgical techniques (e.g., chordae/plication vs. free-edge reinforcement, isolated repair vs. repair plus root re-implantation).
O
Outcome
Long-term clinical outcomes including survival, freedom from valve-related events, and recurrent aortic insufficiency.hard clinical

Main Result

p-value: p=<0.01

Aortic valve repair is a safe surgical option, with better outcomes observed in tricuspid valves, type I/II dysfunction, and when associated with root re-implantation, whereas calcified bicuspid valves have poor results.

Cite This Study

Fattouch et al. (2012) conducted an observational in Aortic insufficiency (n=216). Aortic valve repair vs. Different valve morphologies and repair techniques was evaluated on Freedom from valve-related events (p=<0.01). Aortic valve repair resulted in 91.5% overall late survival, with freedom from valve-related events differing significantly between bicuspid and tricuspid valves (P<0.01).

synapsesocial.com/papers/6a09082aea37c9c7dbe46b7dhttps://doi.org/10.1093/icvts/ivs195
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Valve repair for aortic insufficiency: surgical classification and techniques1997 · 113 citations
  2. 2Repair of Bicuspid Aortic Valves in Patients With Aortic Regurgitation2006 · 96 citations
  3. 3Intermediate-term durability of bicuspid aortic valve repair for prolapsing leaflet11999 · 172 citations
  4. 4Functional Anatomy of Aortic Regurgitation2007 · 175 citations