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May 5, 2015Scandinavian Journal of Medicine and Science in Sports

Effects of acute, intermittent exercise in hypoxic environments on the release of cardiac troponin

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Why the study?

Does acute, intermittent exercise in hypoxic environments increase the release of cardiac troponin in well-trained male marathon runners?

Population

10 well-trained, male marathon runners, mean age 22.1 ± 2.6 years

Comparison

Acute, intermittent exercise in hypoxic… vs Acute, intermittent exercise in normoxic…

Design

Other

Follow-up

24 hours post-exercise

Authors

FLF. LiHebei Normal UniversityYHYang HuDalian Medical UniversityJNJinlei NieMacao Polytechnic University

Discussion

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Implication

Transient troponin rises after hypoxic exercise warrant no clinical alarm in trained athletes; leaves open intensity-driven mechanisms for prospective study.

Structured PICO

Does acute, intermittent exercise in hypoxic environments increase the release of cardiac troponin in well-trained male marathon runners?

P
Population
10 well-trained, male marathon runners, mean age 22.1 ± 2.6 years
I
Intervention
Acute, intermittent exercise in hypoxic environments (FIO2 14.4%, simulated altitude 3000 m) at 90% and 50% normoxic or hypoxic vVO2max
C
Comparator
Acute, intermittent exercise in normoxic environment (FIO2 21.0%) at 90% and 50% normoxic vVO2max
O
Outcome
Release of cardiac troponin (hs-cTnT and cTnI) measured pre- and 0, 2, 4, and 24 h post-exercisesurrogate

Hypoxia alone does not induce greater cardiac troponin release during intermittent exercise, but exercise intensity in hypoxic environments modulates this response.

Cite This Study

Li et al. (2015) studied this question.

synapsesocial.com/papers/6a0908a1a2bc65e38873bde5https://doi.org/10.1111/sms.12463
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serum Cardiac Troponin T in Adolescent Runners: Effects of Exercise Intensity and Duration2009 · 81 citations
  2. 2The kinetics of highly sensitive cardiac troponin T release after prolonged treadmill exercise in adolescent and adult athletes2012 · 93 citations
  3. 3Cardiac Biomarkers and Exercise Duration and Intensity During a Cycle-Touring Event2009 · 45 citations
  4. 4Serum Cardiac Troponin Response in Adolescents Playing Basketball2008 · 62 citations
  5. 5Compensatory vasodilatation during hypoxic exercise: mechanisms responsible for matching oxygen supply to demand2012 · 157 citations