Highlights the potential for false positive troponin I results due to alkaline phosphatase interference, which can lead to misdiagnosis of recurrent acute myopericarditis.
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Clinicians should consider ALP interference in unexplained troponin elevations; case report leaves open systematic validation of assay artifacts.
Introduction: Since there are many manufacturers of cardiac troponin I assays, the true incidence of a false positive result is unknown. The authors report a case of an 18-year-old patient with previous history of recurrent myopericarditis and admitted to hospital twice again with a suspicious of myopericarditis. Conclusion: Troponin I was found to be a false positive and alkaline phosphatase interference was proved to have been the responsible for this.
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Marinheiro et al. (2018) studied this question.
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