Key result
Lower body negative pressure induced greater reflex increases in forearm vascular resistance in men with borderline hypertension compared to normotensive men (8.6 vs 4.5 units; p<0.05).
Why the study?
Does borderline hypertension alter cardiopulmonary baroreflex control of forearm vascular resistance during lower body negative pressure compared to normotensive individuals?
Population
16 men, including 9 with borderline hypertension with blood pressure intermittently above 150/90 mm Hg, and…
Comparison
Lower body negative pressure to reduce… vs Normotensive men undergoing the same…
Design
Case-control
Authors
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Borderline hypertension was associated with augmented baroreflex vasoconstriction; this case-control finding leaves open its role in hypertension progression.
Observational (n=16)
Does borderline hypertension alter cardiopulmonary baroreflex control of forearm vascular resistance during lower body negative pressure compared to normotensive individuals?
Absolute Event Rate: 8.6% vs 4.5%
p-value: p=<0.05
Borderline hypertension is associated with augmented cardiopulmonary baroreflex control of forearm vascular resistance, suggesting an enhanced tonic inhibitory influence of cardiopulmonary baroreceptors.
Mark et al. (1982) conducted an observational in Borderline hypertension (n=16). Lower body negative pressure (LBNP) vs. Normotensive controls was evaluated on Reflex increases in forearm vascular resistance during LBNP-20 (p=<0.05). Lower body negative pressure induced greater reflex increases in forearm vascular resistance in men with borderline hypertension compared to normotensive men (8.6 vs 4.5 units; p<0.05).
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