Key result
Comprehensive Complication Index correlates moderately to strongly with postoperative costs across all operative severity groups.
Why the study?
The Comprehensive Complication Index summarizes postoperative complications, but its relation to hospital costs had not been validated.
Does the Comprehensive Complication Index correlate with overall postoperative costs in patients undergoing general surgery?
Population
1850 patients undergoing surgery at a general surgery service
Comparison
Complications graded by CCI and CDC across surgical severity groups
Design
Prospective observational cohort study
Follow-up
90 days
Authors
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Supports CCI for postoperative cost estimation in general surgery; leaves open prospective validation before guiding resource allocation.
Cohort (n=1,850)
Does the Comprehensive Complication Index correlate with overall postoperative costs in patients undergoing general surgery?
Effect estimate: rs 0.445-0.820
p-value: p=<0.001
The Comprehensive Complication Index demonstrates economic validity by correlating moderately to strongly with overall postoperative costs in general surgery patients.
Llamas et al. (2019) conducted a cohort in Patients undergoing surgery (n=1,850). Comprehensive Complication Index (CCI) vs. Clavien-Dindo classification (CDC) was evaluated on Overall postoperative costs (rs 0.445-0.820, p=<0.001). The Comprehensive Complication Index was moderately to strongly correlated with overall postoperative costs across all operative severity score groups (rs = 0.445-0.820; P<0.001).
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