What is the clinical evidence from this study?

Study design: Cohort. Population: Postoperative morbidity (n=1850). Intervention: Comprehensive Complication Index (CCI) vs. Clavien-Dindo classification (CDC). Primary outcome: Correlation with postoperative stay, prolongation of postoperative stay, readmission, and disability (p=<0.001).

October 10, 2018Annals of SurgeryOpen Access

Clinical Validation of the Comprehensive Complication Index as a Measure of Postoperative Morbidity at a Surgical Department

Q: What are the key findings of this study?

The Comprehensive Complication Index was associated with postoperative stay, readmission, and disability (P<0.001), and was superior to the Clavien-Dindo classification in most models.

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Key result

Comprehensive Complication Index outperforms Clavien-Dindo classification in predicting postoperative stay, readmission, and disability.

P<0.001
n=1,850

Why the study?

Does the comprehensive complication index (CCI) correlate with clinical outcomes better than the Clavien-Dindo classification (CDC) in patients undergoing surgery?

Population

1,850 patients who underwent surgery at a general surgery department during a 1-year study period

Comparison

Comprehensive complication index (CCI) vs Clavien-Dindo classification (CDC)

Design

Cohort

Follow-up

up to 90 days

Authors

RLRoberto de la Plaza LlamasUniversidad de Alcalá JRJosé Manuel RamiaHospital General Universitario de Alicante Doctor Balmis JBJuan M. BellónETH Zurich

Discussion

Member takes

Implication

CCI shows stronger outcome associations than CDC in surgical cohorts; supports further validation but leaves adoption open.

Study Design

Type

Cohort (n=1,850)

Multicenter

Structured PICO

Does the comprehensive complication index (CCI) correlate with clinical outcomes better than the Clavien-Dindo classification (CDC) in patients undergoing surgery?

Population

1,850 patients who underwent surgery at a general surgery department during a 1-year study period

Intervention

Comprehensive complication index (CCI)

Comparator

Clavien-Dindo classification (CDC)

Outcome

Correlation with 4 different clinical outcomes (postoperative stay, prolongation of postoperative stay, readmission, and disability)

Main Result

p-value: p=<0.001

Cite This Study

Llamas et al. (2018) conducted a cohort in Postoperative morbidity (n=1,850). Comprehensive Complication Index (CCI) vs. Clavien-Dindo classification (CDC) was evaluated on Correlation with postoperative stay, prolongation of postoperative stay, readmission, and disability (p=<0.001). The Comprehensive Complication Index was associated with postoperative stay, readmission, and disability (P<0.001), and was superior to the Clavien-Dindo classification in most models.

synapsesocial.com/papers/6a090a2529af591ab701751f https://doi.org/10.1097/sla.0000000000002839

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Clinical Validation of the Comprehensive Complication Index as a Measure of Postoperative Morbidity at a Surgical Department

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Cite This Study

Clinical Validation of the Comprehensive Complication Index as a Measure of Postoperative Morbidity at a Surgical Department

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider