PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
October 4, 2025Heart Rhythm6 citationsOpen Access

The extravascular ICD: Evolving paradigms in sudden death prevention

View Full Paper
TMTimothy M. MarkmanTCThomas Callahan

Key Result

The extravascular ICD (EV-ICD) demonstrates high defibrillation success, effective antitachycardia pacing, and low complication rates in patients at risk of lethal ventricular arrhythmias.

Structured PICO

P
Population
Patients at risk of lethal ventricular arrhythmias, particularly those without previous sternotomy or pacing indications for bradycardia or resynchronization, and at elevated risk of transvenous lead-related complications
I
Intervention
Extravascular implantable cardioverter-defibrillator (EV-ICD)

The EV-ICD is an effective and attractive option for sudden cardiac death prevention in patients without pacing indications or prior sternotomy, offering defibrillation and antitachycardia pacing without transvenous leads.

Limitations

  • Unknowns regarding patient selection and durability
  • Lack of long-term outcomes
  • Further research is needed to define long-term outcomes

Abstract

Implantable cardioverter-defibrillators (ICDs) remain the mainstay of prevention of sudden cardiac death in patients at risk of lethal ventricular arrhythmias. Current ICD systems use leads placed via transvenous, subcutaneous, or surgical epicardial approaches. The extravascular ICD (EV-ICD) is a novel device that avoids transvenous lead placement while enabling defibrillation and limited pacing including antitachycardia pacing. This review summarizes key features of the EV-ICD system and synthesizes published trial and real-world evidence. Collectively, these studies demonstrate high defibrillation success, effective antitachycardia pacing, and low complication rates. The EV-ICD is an attractive option for patients without previous sternotomy or pacing indications for bradycardia or resynchronization, particularly those at an elevated risk of transvenous lead-related complications. Further research is needed to define long-term outcomes and refine patient selection. This review offers an evidence-based evaluation of the EV-ICD's role in contemporary arrhythmia management including limitations of the device and unknowns regarding patient selection and durability.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Markman et al. (2025) conducted a review in Sudden cardiac death prevention. Extravascular ICD (EV-ICD) was evaluated. The extravascular ICD (EV-ICD) demonstrates high defibrillation success, effective antitachycardia pacing, and low complication rates in patients at risk of lethal ventricular arrhythmias.

synapsesocial.com/papers/6a091c951d1abd907d15f71ehttps://doi.org/10.1016/j.hrthm.2025.09.038
Ask AI
Helpful
Bookmark
Share
View Full Paper