Key result
A systematic review of retrosternal extravascular ICDs reported an outcome of 6/73 for the intercostal EV-ICD lead, though full results were truncated in the abstract.
Why the study?
To assess acute outcomes in patients implanted with a retrosternal extravascular implantable cardioverter-defibrillator.
Systematic Review
This systematic review aims to assess the acute safety and implant characteristics of retrosternal extravascular ICDs, though the results are missing from the provided text.
Acute safety of retrosternal EV-ICDs appears favorable in cohorts; leaves open need for randomized confirmation of efficacy and durability.
INTRODUCTION: Implantable cardioverter-defibrillators (ICD) terminate potentially deadly ventricular arrhythmias in at-risk patients. Retrosternal extravascular ICDs (EV-ICD) place a lead in the mediastinal space to provide both shock and antitachycardia pacing therapy without the need for venous access. A systematic review was performed to assess acute outcomes in patients implanted with a retrosternal EV-ICD. METHODS: A query of EMBASE and MEDLINE databases was performed to identify unique retrosternal EV-ICD cohort studies published between JAN-1-2020 and JAN-31-2026. Two known retrosternal EV-ICDs were included, the market-approved Medtronic substernal EV-ICD system and investigational AtaCor intercostal EV-ICD lead. Procedure and defibrillation testing details and acute safety data were collected. RESULTS: = 6/73) for the intercostal EV-ICD lead. CONCLUSIONS: : www.crd.york.ac.uk/prospero identifier is CRD420261328371.
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Crossley et al. (2026) conducted a systematic review in Ventricular arrhythmias. Retrosternal extravascular implantable cardioverter-defibrillators (EV-ICD) was evaluated on Acute outcomes, procedure and defibrillation testing details, and acute safety. A systematic review of retrosternal extravascular ICDs reported an outcome of 6/73 for the intercostal EV-ICD lead, though full results were truncated in the abstract.
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